Benzedrine, in the form of inhalers and later tablets, was readily available over the counter until the 1950s. Marketed under this brand name by Smith, Kline & French (the company that was to become part of GlaxoSmithKline), the drug was initially used as a bronchodilator.
However, people who needed help to breathe soon discovered that the innocuous inhaler had a potent stimulant effect. By 1949, many stories had been reported of the drug being used for recreational purposes, as well as as an appetite suppressant.
A decade later, “bennies” (as they came to be known) were reclassified as a controlled substance. Benzedrine was then replaced by non-prescription inhalers containing propylhexedrine, which was sold as Benzedrex.